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Infectious diseases and prions 

Infectious diseases and prions
Infectious diseases and prions

Davidson H. Hamer

and Zulfiqar A. Bhutta

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date: 27 January 2022

During the last century, substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases. Nevertheless the burden of infectious diseases remains substantial in resource-limited areas of the world, in particular among children under 5 years of age. Lower respiratory tract infections, diarrhoeal diseases, malaria, and neonatal infections (sepsis, pneumonia, and meningitis) continue to rank among the most common causes of morbidity and mortality among young children. HIV/AIDS, tuberculosis, and lower respiratory tract infections are major causes of morbidity and mortality among adults. This chapter reviews the global burden of common infectious diseases in children and adults, determinants of the high infectious disease burden in resource-poor countries, and important aspects of the clinical manifestations, diagnosis, and treatment of the handful of infectious diseases that account for the major share of morbidity and mortality in children and adults worldwide.

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