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Chronic cerebrospinal venous insufficiency 

Chronic cerebrospinal venous insufficiency
Chronic cerebrospinal venous insufficiency

Paolo Zamboni

, Sergio Gianesini

, and Erica Menegatti

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date: 04 July 2020

Chronic cerebrospinal venous insufficiency is a syndrome characterized by stenosis or occlusion of the internal jugular and/or azygous veins with disturbed flow and formation of collateral venous channels. This impairs venous drainage of the brain. The venous pathology is related to segmental hypoplasia or, more frequently, to intraluminal defects (webs, fixed valve leaflets, membranes) or compression. Chronic cerebrospinal venous insufficiency has been particularly studied in multiple sclerosis, where the majority of studies indicate a higher prevalence with respect to controls. In this field venoplasty seems safe and has been suggested to improve some outcome parameters, although higher quality evidence is required.

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