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Non-atherosclerotic lower limb ischaemia 

Non-atherosclerotic lower limb ischaemia
Non-atherosclerotic lower limb ischaemia

Robert J. Hinchliffe

, Mart Bender

, and Goof Schep

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date: 04 July 2020

Non-atherosclerotic arterial disease of the lower limbs is rare. Healthcare professionals are more familiar with atherosclerotic disease of the lower limbs and, therefore, patients who have non-atherosclerotic disease frequently present late, after they have been investigated for a wide range of other conditions. There is a wide spectrum of pathologies from congenital to acquired conditions. Some of the diseases, such as fibromuscular dysplasia, may have other arterial involvement, whilst others are confined to specific arteries of the lower limb. Although some of the conditions have a benign course, most are associated with significant reduction in quality of life in a relatively young, otherwise fit population. Vascular surgeons should therefore be aware of the most notable of these rare conditions. Specifically, they should be able to identify them in everyday clinical practice, understand their natural history and the indications for and outcomes of surgical intervention.

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