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Vascular graft infection 

Vascular graft infection
Chapter:
Vascular graft infection
Author(s):

Morgyn Warner

, Renjy Nelson

, and Chuan Lim

DOI:
10.1093/med/9780199658220.003.0012
Page of

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date: 18 September 2019

Vascular graft infections are an uncommon, but severe complication of revascularization procedures. Infections are usually caused by organisms present on the skin, which are introduced with a new graft at the time of surgery. The development of a biofilm on the graft surface makes infection difficult to eradicate due to diminished access of antibiotics to biofilm-associated microorganisms. Vascular graft infections may be diagnosed by pathognomonic clinical signs and symptoms, imaging studies, and microbiological investigations. Management of graft infection depends on the location and extent of the infection, and generally requires a combination of surgical debridement and antibiotic therapy. Improvements in diagnostic techniques, graft biomaterials and innovations in treatment of biofilm-associated infections could further decrease the incidence and morbidity associated with graft infections.

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