Show Summary Details
Page of

Spontaneous intracerebral haemorrhage 

Spontaneous intracerebral haemorrhage
Chapter:
Spontaneous intracerebral haemorrhage
Author(s):

Peter Bodkin

DOI:
10.1093/med/9780199656400.003.0020
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 15 April 2021

Low grade gliomas are diffusely infiltrating brain tumours, comprising: WHO grade II astrocytomas, Grade II oligodendrogliomas and oligoastrocytomas. Despite the name, low grade gliomas are not benign lesions. These tumours have growth potential and can undergo malignant transformation to high grade tumours. Seizures, often simple partial, complex partial or generalised tonic clonic, are the most common presentation in 80-90% of patients with LGG, followed by headaches and focal deficits. Close proximity to the cortex is likely to be responsible for this picture. Death is usually due to malignant change. With recent advances in neurobiology, diagnostic imaging, surgical technology and adjuvant therapies the management of these tumours has undergone a paradigm shift. This chapter explores the diagnosis and management options for low grade glioma. If the tumour has relatively discrete margins in brain tissue, a macroscopic resection may be possible without compromising function, and maximum safe surgical resection of all hyper intense tissue on FLAIR sequences should be attempted. This will improve overall and progression free survival and gives improved seizure control, as well as providing better tumour sampling for histology.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.