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Chemical carcinogens 

Chemical carcinogens
Chapter:
Chemical carcinogens
Author(s):

Paula A. Oliveira

DOI:
10.1093/med/9780199656103.003.0016_update_001

Updates

States the tests available to identify chemical carcinogens

Includes updated available techniques to detect adduct formation after chemical carcinogens exposition

Updated on 25 May 2017. The previous version of this content can be found here.
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date: 19 August 2019

The development of cancer associated with exposure to chemical carcinogens is a reality and existing knowledge of these cancers is based on epidemiological, in vivo, and in vitro studies. Chemical carcinogens are present virtually everywhere and humans can be exposed to these compounds in food, air, water, their environment, or their workplace. This chapter is concerned with the main types of exogenous chemical carcinogens, how they are classified and their modes of action, absorption, and metabolism, as well as the principal tests available for evaluating their carcinogenicity. Only exogenous chemicals are considered in this chapter, since exogenous chemical carcinogens may be the major contributors to human cancer.

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