Show Summary Details
Page of

Principles of drug therapy: focus on opioids 

Principles of drug therapy: focus on opioids
Principles of drug therapy: focus on opioids

Ruth Branford

, Emily Wighton

, and Joy Ross

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 07 May 2021

Key principles of clinical pharmacology inform prescribing in palliative care. The use of opioid therapy for pain in populations with serious medical illness exemplifies the relevance of these principles. Concepts include the differences among efficacy, effectiveness, and cost-effectiveness; the nature of a benefit-to-risk analysis; and the meaning of pharmacokinetic variation and pharmacokinetic-pharmacodynamic relationships. This information complements related information about opioid therapy, including best practices during routine care and the role of opioid switching, opioid abuse, and opioid prescribing at the end of life. More extensive information about general pharmacology is available in comprehensive pharmacology textbooks.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.