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Palliation of nausea and vomiting 

Palliation of nausea and vomiting
Palliation of nausea and vomiting

Janet R. Hardy

, Paul Glare

, Patsy Yates

, and Kathryn A. Mannix

Page of

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date: 07 May 2021

Nausea and vomiting (NV) are unpleasant symptoms reported as highly distressing by sufferers and have a significant impact on activities of daily living. The prevalence of nausea is 6-68% in people with advanced cancer, 17-48% in heart disease, 30-43% in renal disease, and 43-49% in people with AIDS and is not always associated with vomiting. Several multifactorial clinical syndromes can contribute to NV in patients with advanced illness. Two strategies have been proposed for the management of nausea and vomiting: the mechanistic and the empirical approach. Most of the evidence supporting the use of antiemetic drugs in palliative care has been extrapolated from trials of chemotherapy- and radiotherapy-induced NV. An ideal measurement tool for the assessment of NV and retching has yet to be developed. Inherent in the management of NV is to maximize treatment of those symptoms commonly associated with NV.

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