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Neurochemistry of cognition 

Neurochemistry of cognition
Chapter:
Neurochemistry of cognition
Author(s):

Trevor W. Robbins

DOI:
10.1093/med/9780199655946.003.0009
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date: 30 May 2020

Roles for the main fast signalling and neuromodulatory chemical neurotransmitter systems in cognitive function are defined both for humans and other animals. Glutamate and GABA systems are implicated in the functioning of neural networks that mediate learning and other cognitive functions through neuronal processes such as long-term potentiation. These networks are shown to be modulated by the ascending monoaminergic systems, including dopamine, noradrenaline, and serotonin, mediating effects of arousal and motivation on cognition. Additionally, possible roles for neuropeptide neurotransmitters are identified, including those in social cognition. Possible implications for the treatment of neuropsychiatric disorders are explored as well, wherever appropriate.

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