Show Summary Details
Page of

Autoimmune encephalitis 

Autoimmune encephalitis
Chapter:
Autoimmune encephalitis
Author(s):

Sarosh R. Irani

, Thomas D. Miller

, and Angela Vincent

DOI:
10.1093/med/9780199655946.003.0028
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 07 June 2020

This chapter describes the clinical and paraclinical features of an expanding group of conditions associated with potentially pathogenic autoantibodies. These autoantibodies target the extracellular domains of critical neuronal proteins. The associated conditions are increasingly recognized as a cause of cognitive and behavioural disturbances in children and adults, and often associate with a number of other clinical features including seizures and movement disorders. Importantly, these conditions show often marked improvements with immunotherapies. Finally, this chapter discusses the putative mechanisms underlying the pathophysiology of these conditions, the associated cognitive deficits, and MRI findings which suggest these diseases could be used for the study of broader neurosciences questions.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.