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Vascular cognitive impairment 

Vascular cognitive impairment
Vascular cognitive impairment

Geert Jan Biessels

and Philip Scheltens

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date: 01 August 2021

The aim of this chapter is to give an overview of cognitive impairment due to cerebrovascular disease. While cerebrovascular disease is clearly an important cause and contributor to cognitive impairment, there is substantial heterogeneity both in the manifestations of cognitive dysfunction in the context of vascular disease and in underlying vascular pathologies. It has proven to be a challenge to deal with this heterogeneity in diagnostic criteria that can be readily and unequivocally applied in clinical practice. This chapter will start by briefly reviewing the evolution of diagnostic criteria for vascular cognitive impairment. This will be followed by an overview of the neuropathology and neuroimaging features of vascular cognitive impairment (VCI). The final section of the chapter addresses clinical evaluation and management of VCI.

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