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The sepsis resuscitation bundle 

The sepsis resuscitation bundle
Chapter:
The sepsis resuscitation bundle
Author(s):

Adham Khalek

DOI:
10.1093/med/9780199654093.003.0001
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date: 24 September 2021

This chapter provides an overview of the recognition and treatment of Sepsis in the acute phase. It discusses the biochemical and physiological parameters which assist in the recognition and diagnosis of sepsis.

This chapter examines the evidence for the early use of antibiotics and discusses the ED infrastructure required to ensure this is possible. Fungal infections are also discussed and risk factors for such infections are highlighted.

The evidence behind the concept of early goal-directed therapy and care bundles is discussed in relation to the early treatment of sepsis. The use of noradrenaline for patients with hypotension not responsive to fluids is described as advised by the College of Emergency Medicine. Interventions are discussed in relation to reduction in mortality for this group of patients. Ongoing trials in the area of sepsis management are recognized.

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