- Foreword
- Preface
- Abbreviations
- Contributors
- Chapter 1 The 2016 revision of the WHO classification of tumours of the central nervous system
- Chapter 2 Astrocytic tumours: pilocytic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma
- Chapter 3 Astrocytic tumours: diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, and gliomatosis cerebri
- Chapter 4 Oligodendroglial tumours
- Chapter 5 Ependymal tumours
- Chapter 6 Choroid plexus tumours
- Chapter 7 Other neuroepithelial tumours: astroblastoma, angiocentric glioma, and chordoid glioma
- Chapter 8 Neuronal and mixed neuronal–glial tumours
- Chapter 9 Embryonal and pineal tumours
- Chapter 10 Tumours of the cranial nerves
- Chapter 11 Meningiomas
- Chapter 12 Other tumours of the meninges
- Chapter 13 Tumours of the haematopoietic system
- Chapter 14 Germ cell tumours
- Chapter 15 Familial tumour syndromes: neurofibromatosis, schwannomatosis, rhabdoid tumour predisposition, Li–Fraumeni syndrome, Turcot syndrome, Gorlin syndrome, and Cowden syndrome
- Chapter 16 Familial tumour syndromes: von Hippel–Lindau disease
- Chapter 17 Familial tumour syndromes: tuberous sclerosis complex
- Chapter 18 Pituitary tumours
- Chapter 19 Metastatic brain tumours
- Chapter 20 Metastatic tumours: spinal cord, plexus, and peripheral nerve
- Chapter 21 Neoplastic meningitis: metastases to the leptomeninges and cerebrospinal fluid
- Index
(p. 223) Metastatic tumours: spinal cord, plexus, and peripheral nerve
- Chapter:
- (p. 223) Metastatic tumours: spinal cord, plexus, and peripheral nerve
- Author(s):
David Schiff
, Jonathan Sherman
, and Paul D. Brown
- DOI:
- 10.1093/med/9780199651870.003.0020
Systemic cancers produce substantial neurological morbidity when they spread to the spinal epidural space, producing epidural spinal cord compression—a neurological emergency. Less often, metastases spread directly to spinal cord parenchyma to manifest as intramedullary spinal cord metastasis or result in peripheral nerve dysfunction via compression of the brachial, lumbosacral, or, rarely, the cervical plexus. This chapter reviews the clinical manifestations and risk factors for development of these entities, the diagnostic approach, management options including the role of surgery, radiation (including stereotactic body radiation therapy), and chemotherapy, as well as the neurological prognosis.
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- Foreword
- Preface
- Abbreviations
- Contributors
- Chapter 1 The 2016 revision of the WHO classification of tumours of the central nervous system
- Chapter 2 Astrocytic tumours: pilocytic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma
- Chapter 3 Astrocytic tumours: diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, and gliomatosis cerebri
- Chapter 4 Oligodendroglial tumours
- Chapter 5 Ependymal tumours
- Chapter 6 Choroid plexus tumours
- Chapter 7 Other neuroepithelial tumours: astroblastoma, angiocentric glioma, and chordoid glioma
- Chapter 8 Neuronal and mixed neuronal–glial tumours
- Chapter 9 Embryonal and pineal tumours
- Chapter 10 Tumours of the cranial nerves
- Chapter 11 Meningiomas
- Chapter 12 Other tumours of the meninges
- Chapter 13 Tumours of the haematopoietic system
- Chapter 14 Germ cell tumours
- Chapter 15 Familial tumour syndromes: neurofibromatosis, schwannomatosis, rhabdoid tumour predisposition, Li–Fraumeni syndrome, Turcot syndrome, Gorlin syndrome, and Cowden syndrome
- Chapter 16 Familial tumour syndromes: von Hippel–Lindau disease
- Chapter 17 Familial tumour syndromes: tuberous sclerosis complex
- Chapter 18 Pituitary tumours
- Chapter 19 Metastatic brain tumours
- Chapter 20 Metastatic tumours: spinal cord, plexus, and peripheral nerve
- Chapter 21 Neoplastic meningitis: metastases to the leptomeninges and cerebrospinal fluid
- Index