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Extending the evidence for immunotherapy to the management of children with house-dust-mite-triggered asthma 

Extending the evidence for immunotherapy to the management of children with house-dust-mite-triggered asthma
Chapter:
Extending the evidence for immunotherapy to the management of children with house-dust-mite-triggered asthma
Author(s):

Roy Gerth van Wijk

DOI:
10.1093/med/9780199651559.003.0049
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date: 15 November 2019

Hyposensitisation with Dermatophagoides pteronyssinus tyrosine absorbate in asthmatic children with bronchial sensitivity to D. pteronyssinus was effective in a 12-month double-blind controlled clinical trial. Compared with controls, treated children used a smaller quantity of drugs while maintaining clinical and lung function improvements. In most children who improved there was no change in immediate response to D. pteronyssinus on bronchial provocation test, but the late reaction was lost in half the patients and these showed the greatest improvement in symptoms.

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