Show Summary Details
Page of

The dawn of molecular allergology 

The dawn of molecular allergology
Chapter:
The dawn of molecular allergology
Author(s):

Hannah Gould

DOI:
10.1093/med/9780199651559.003.0037
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 18 November 2019

Studies of the nature of the antibodies associated with isologous skin sensitizing activity have indicated the presence of a previously unrecognized immunoglobulin in human serum. The immunoglobulin was identified by virtue of specific antigenic determinants. Independently, a protein with similar antigen characteristics was identified both in the serum of a patient with multiple myeloma and in normal serum. It is proposed that the normal protein and antigenically related myeloma proteins shall be designated IgE or γ‎E, and the heavy polypeptide chains of these molecules be designated ε‎ (epsilon)-chains, in accordance with Nomenclature for Human Immunoglobulins. This replaces the previous usage of γ‎E-globulin and IgND.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.