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Penicillin allergy: a model for practical clinical translational science 

Penicillin allergy: a model for practical clinical translational science
Chapter:
Penicillin allergy: a model for practical clinical translational science
Author(s):

Lanny Rosenwasser

DOI:
10.1093/med/9780199651559.003.0034
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date: 18 November 2019

Direct skin tests and passive transfer tests were compared as to their abilities to detect skin-sensitizing antibody (SSA) to penicillin haptens in man. Direct skin tests were found to be a generally more sensitive detector of SSA. However, in some cases where penicillin therapy had been given recently, and the immune response to penicillin was still evolving, direct skin tests were negative in the face of positive passive transfer tests of the same specificity.

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