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RAST: Iconic test for allergic sensitization 

RAST: Iconic test for allergic sensitization
Chapter:
RAST: Iconic test for allergic sensitization
Author(s):

Shuaib Nasser

DOI:
10.1093/med/9780199651559.003.0032
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date: 22 July 2019

An in-vitro method, called the radioallergosorbent test, has been developed for the detection of allergen-specific antibodies of a new immunoglobulin class, provisionally called IgND. Antibodies to 14 different allergens were detected in sera of allergic patients. A 96% agreement was obtained between results from provocation tests and the in-vitro test for allergy. The results strongly support the hypothesis that reagins belong to the immunoglobulin class IgND. The method described might become of great importance for the clinical diagnosis of hypersensitivity to various allergens.

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