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The relationship between mast cells and histamine 

The relationship between mast cells and histamine
Chapter:
The relationship between mast cells and histamine
Author(s):

Michael Kaliner

DOI:
10.1093/med/9780199651559.003.0024
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date: 18 November 2019

The amount of histamine that can be extracted from various body tissues has been studied extensively in recent years. However, little attention has been paid to the histology of tissues rich in histamine or to the changes which accompany histamine release. Since it is now believed that heparin in all species is produced by tissue mast cells . . . it seemed of interest to determine whether histamine also could arise from tissue mast cells. . . . Further evidence that substantial amounts of histamine are contained in, and can be released by, tissue mast cells is presented in this paper.

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