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Bovet’s Nobel Prize-winning discovery of antihistamines 

Bovet’s Nobel Prize-winning discovery of antihistamines
Chapter:
Bovet’s Nobel Prize-winning discovery of antihistamines
Author(s):

Martin K Church

and Marcus Maurer

DOI:
10.1093/med/9780199651559.003.0020
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date: 17 October 2019

We searched systematically for the existence of histamine antagonists, thinking that this study would provide a new way to address more points in the physiology of this hormone, and would be likely to have therapeutic applications. We report the first results obtained with many substances containing a phenolic ether function. We saw, indeed, that there are many products in this series which can protect guinea pigs from toxic doses of histamine.

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