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A serendipitous discovery 

A serendipitous discovery
Chapter:
A serendipitous discovery
Author(s):

Madeleine Ennis

DOI:
10.1093/med/9780199651559.003.0011
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date: 19 November 2019

It has been made clear . . . that the peculiarly and rapidly fatal character of anaphylactic shock in the guinea-pig depends on the valve-like closure of the bronchioles . . . My own experiments began some time ago with the accidental observation of the extraordinary sensitiveness to horse serum of certain isolated uteri, which I was using for another purpose. Enquiry revealed the fact that the guinea-pigs from which they were taken were all survivors from antitoxin standardisations. Testing the uterus from a normal guinea-pig I found no response of the kind.

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