Show Summary Details
Page of

Research in organ donors: future directions 

Research in organ donors: future directions
Research in organ donors: future directions

Claus Niemann

and Andrea Olmos

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 03 August 2020

The disparity between the demand for donor organs and supply of organs for transplantation is significant and will likely continue to grow in the coming years. Maximizing the number of transplantable organs from the deceased donor pool via novel donor management strategies is likely the best method for increasing the number of organs available for transplantation, yet deceased donor management is one of the most neglected areas in transplantation medicine and research. Multiple studies have demonstrated that aggressive donor management protocols increase the quantity and quality of organs available for transplantation; however, only a handful of these are intervention trials. Several factors create barriers to conducting randomized prospective studies in deceased organ donors, including the lack of an established research infrastructure. Ethical and regulatory challenges surrounding informed consent for the deceased donor and potential organ recipients are also substantial obstacles to conducting clinical trials. These and other obstacles must be addressed in order to advance research efforts in transplant medicine and bridge the gap between organ supply and demand.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.