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Liver transplantation: anaesthesia and perioperative care 

Liver transplantation: anaesthesia and perioperative care
Liver transplantation: anaesthesia and perioperative care

John R. Klinck

and Andre De Wolf

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date: 22 October 2019

Severe liver disease affects all organ systems, and the perioperative management of the liver transplant recipient presents a major challenge, even after more than 30 years of improvements in clinical practice. Today’s recipients are older and have more advanced disease and more comorbidities than ever before. Many grafts now come from marginal or non-heart-beating donors, adding to perioperative risk, and even those from living donors present special difficulties. Cardiovascular instability, haemorrhage, and severe electrolyte, acid-base, and haemostatic derangements are routine features of this procedure. This chapter summarizes the pathophysiology of liver disease and the surgical techniques used in transplantation and gives a comprehensive overview of current anaesthetic practice.

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