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Sexual differentiation 

Sexual differentiation
Chapter:
Sexual differentiation
Author(s):

Enda McVeigh

, John Guillebaud

, and Roy Homburg

DOI:
10.1093/med/9780199650682.003.0001
Page of

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date: 05 May 2021

Key stages of fetal sex differentiation

The SRY gene

Other genes involved in sex determination

Abnormal embryological development—intersex conditions

Hermaphroditism

Mullerian anomalies

Hand–foot–genital syndrome

Incomplete regression of the Wolffian system

Further information

Genetic sex is determined at the moment of conception by the presence or absence of the Y chromosome, and after week 6 of fetal life it will guide the subsequent development of the fetus down one of two standard pathways—male or female (see ...

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