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Contents
- Chapter 1 Antibody pre-history: The emergence of empirical immunology
- Chapter 2 Pre-molecular immunology: The dawn of mechanism
- Chapter 3 Structural chemistry: Locks, keys, and colloids
- Chapter 4 The foundations of antibody-antigen recognition emerge
- Chapter 5 The cellular reformation
- Chapter 6 The molecular path unfolds
- Chapter 7 Uncovering the origins of antibody diversity
- Chapter 8 Immunoglobulin constant regions
- Chapter 9 Effector functions of constant regions
- Chapter 10 Transmission and catabolism of IgG
- Chapter 11 The structural context of antibody diversity
- Chapter 12 Monoclonal antibodies and the mechanisms of hypermutation
- Chapter 13 Antibody structure prediction and development of humanization strategies
- Chapter 14 Antibody engineering: Improving on natural immunity
- Chapter 15 Therapeutic antibodies Case study I: Prevention of respiratory syncytial virus illness
- Chapter 16 Therapeutic antibodies Case study II: Targeting breast cancer
- Chapter 17 Antibodies: The therapeutic future