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Methodological considerations in surgical trials 

Methodological considerations in surgical trials
Methodological considerations in surgical trials

Graham J. MacKay

, Richard G. Molloy

, and Patrick J. O’Dwyer

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 03 December 2020

1.1 Introduction 2

1.2 Designs for surgical trials 3

1.3 Specific design issues in surgical trials 7

1.4 Issues in the conduct of randomized controlled trials 16

1.5 Analysis of surgical trials 18

1.6 Other issues in surgical trials 22

1.7 Summary 23

This new volume will provide interested groups with a valuable guide to surgical research that changed practice—landmark studies that improved professional practice and outcomes for patients undergoing surgical procedures. It will also be a useful resource for researchers trying to build the best designs for future surgical studies, giving them insights into how to overcome the challenges inherent in conducting high-quality surgical research....

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