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Neuroimmune interactions and pain during postnatal development 

Neuroimmune interactions and pain during postnatal development
Chapter:
Neuroimmune interactions and pain during postnatal development
Author(s):

David Vega-Avelaira

and Simon Beggs

DOI:
10.1093/med/9780199642656.003.0007
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date: 16 September 2021

The immune system is essential for identifying and mounting defensive responses to tissue damage and infection. In addition, it is increasingly recognized that interactions between immune cells and nociceptive pathways can modulate pain sensitivity. The role and function of immune cells in the central nervous system changes during postnatal development, and as a result, the impact of neuroimmune interactions on pain signalling varies with both age and the type of injury.

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