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Research in anaesthesia 

Research in anaesthesia
Chapter:
Research in anaesthesia
Author(s):

Gary Minto

, and J. Robert Sneyd

DOI:
10.1093/med/9780199642045.003.0038
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date: 22 November 2019

Clinicians need critical appraisal skills to weigh up the quality of the literature and to decide whether it has implications for their practice. Every belief in medicine is a construct created from the limited information available and carries a degree of uncertainty. A centralized approach to research identifies the highest priority areas of uncertainty so as to bring about the most improvement for the largest number of patients. This patient-centred model classifies studies into basic science, translational, and clinical research. Adequately powered mega-trials are required to bridge the translational gap between efficacy (does a treatment work?) and effectiveness (does a treatment work when applied in ordinary clinical practice?). There is a paucity of these in perioperative medicine.

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