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Nervous and musculoskeletal systems 

Nervous and musculoskeletal systems
Nervous and musculoskeletal systems

Jeremy Prout

, Tanya Jones

, and Daniel Martin

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date: 15 April 2021

This chapter outlines the basic science related to the nervous and musculoskeletal systems which particularly apply to the conduct of anaesthesia. Consciousness, sleep and anaesthetic depth are discussed with the measurement of anaesthetic depth using bispectral index and evoked potentials. Factors which influence cerebral blood flow and intracerebral pressure are detailed, allowing understanding of neuroanaesthesia techniques. Pharmacological and anaesthetic management of seizures is also described. Diseases affecting the autonomic nervous system, testing for these disorders and the implication for anaesthesia are included. Physiological consequences of spinal cord injury with patterns of injury are described. Neuromuscular blocking agents, monitoring of blockade and implications for patients with neuromuscular disease is also explained.

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