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Non-motor Symptom Management in Parkinson’s Disease 

Non-motor Symptom Management in Parkinson’s Disease
Non-motor Symptom Management in Parkinson’s Disease

Eduardo Tolosa

, Carles Gaig

, and Lillian Acevedo

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date: 05 December 2020

Interest in non-motor symptoms (NMS) in Parkinson’s disease (PD) has increased in recent years. Unlike the classic motor symptoms that can respond to dopaminergic treatment and functional neurosurgery, NMS generally fail to improve with currently available treatments. Consequently, they are a major source of disability and frequently impact negatively upon the patient’s quality of life. Interest in NMS in PD has also increased after it became evident that some NMS antedate the classic motor signs of PD. An understanding of the nature of NMS in pre-motor PD may provide information about the causes of PD and aid in the study of drugs with neuroprotective potential.

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