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Neoplastic disease and other non-parathyroid causes of hypercalcaemia 

Neoplastic disease and other non-parathyroid causes of hypercalcaemia
Chapter:
Neoplastic disease and other non-parathyroid causes of hypercalcaemia
Author(s):

Roger Smith

and Paul Wordsworth

DOI:
10.1093/med/9780199607990.003.0008
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date: 05 December 2020

Malignant disease is the major non-parathyroid cause of hypercalcaemia. Cancer cells can resorb bone directly (as metastases) or indirectly (particularly by the action of PTHrP (PTHLP)). The effects of multiple myeloma are complex. Other non-parathyroid causes of hypercalcaemia include granulomas, drugs and Williams syndrome. This chapter also deals with the treatment of hypercalcaemia.

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