Show Summary Details
Page of

Fibrous dysplasia 

Fibrous dysplasia
Chapter:
Fibrous dysplasia
Author(s):

Roger Smith

and Paul Wordsworth

DOI:
10.1093/med/9780199607990.003.0015
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 23 February 2020

Fibrous dysplasia is a rare heterogenous disorder resulting from postzygotic activating mutation of the GNAS gene. Its main effect is on the skeleton. According to the distribution of the mutation this may be monostotic or polyostotic or, when widespread, the McCune–Albright syndrome. Treatment with bisphosphonates and denosumab is described.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.