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Stuart Crisp

and Jo Rainbow

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date: 31 July 2021

Pathophysiology 88

Causes 89

Assessment and treatment 90

Shock is the inadequate perfusion of the body's vital organs. Perfusion is dependent on:

cardiac output;

stroke volume (blood expelled from left ventricle);

heart rate.

Factors that reduce any of these basic functions may eventually lead to shock. The result is failure to supply oxygen and substrate to cells as well as impaired removal of their waste products. Anaerobic metabolism and tissue acidosis will result. If there is insufficient compensation to reverse these changes, multiple end-organ failure and death will follow....

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