Show Summary Details
Page of

Pain mechanisms in the elderly 

Pain mechanisms in the elderly
Pain mechanisms in the elderly

Khalil Ullah Shibli

and Sabina Shibli

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 05 July 2020

This chapter focuses on the mechanisms of pain and includes definitions, types, and descriptions of pain, how pain is initiated or caused, detected, transmitted, facilitated, inhibited, modulated, and finally perceived. The current theories on the underlying mechanisms are detailed and the anatomical, physiological, and functional changes in pain perception in the elderly are described. There is a clear review of pain processing with age against the background of occupational and mechanical pain followed by increasingly painful degenerative conditions such as arthritis. The loss of myelinated fibres in peripheral nerves is described with the predictable effects on pain modulation. The loss of neuropeptides with predominately inhibitory action and the manner in which this leads to a fall in pain tolerance are reviewed. Similar changes in the autonomic nervous system are described that predispose the elderly to chronic pain syndromes.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.