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Autoimmunity in liver disease 

Autoimmunity in liver disease
Chapter:
Autoimmunity in liver disease
Author(s):

Gavin P Spickett

DOI:
10.1093/med/9780199603244.003.0008
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date: 24 August 2019

Primary biliary cirrhosis (PBC)

Autoimmune hepatitis

Primary sclerosing cholangitis

PBC is a disease of older women (90% of patients are female).

Clinical features include initially:

profound fatigue starting in the prodrome

intense itch

arthralgia.

With disease progression:

hepatosplenomegaly...

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