- Section 1 ICU organization and management
- Section 2 Pharmacotherapeutics
- Section 3 Resuscitation
- Section 4 The respiratory system
- Section 5 The cardiovascular system
- Section 6 The gastrointestinal system
- Section 7 Nutrition
- Section 8 The renal system
- Section 9 The neurological system
- Section 10 The metabolic and endocrine systems
- Section 11 The haematological system
- Section 12 The skin and connective tissue
- Section 13 Infection
- Section 14 Inflammation
- Section 15 Poisoning
- Section 16 Trauma
- Section 17 Physical disorders
- Part 17.1 Drowning
- Part 17.2 Electrocution
- Part 17.3 Altitude- and depth-related disorders
- Part 17.4 Temperature related disorders
- Chapter 352 Pathophysiology and management of fever
- Chapter 353 Pathophysiology and management of hyperthermia
- Chapter 354 Pathophysiology and management of hypothermia
- Part 17.5 Rhabdomyolysis
- Section 18 Pain and sedation
- Section 19 General surgical and obstetric intensive care
- Section 20 Specialized intensive care
- Section 21 Recovery from critical illness
- Section 22 End-of-life care
(p. 1682) Temperature related disorders
Core body temperature is strictly regulated by autonomic and behavioural compensatory adaptations and an increase may represent a physiological stereotypical controlled response to septic and inflammatory conditions, or an uncontrolled drop in the hypothalamic thermoregulatory threshold. Fever has been demonstrated to be a potential mechanism of intrinsic resistance against infectious disease playing a pivotal role in the human evolution. High temperature may be detrimental during oxygen delivery-dependent conditions and in a neurological population. Despite this evidence, a definitive conclusion, between the association of fever and the outcome in critically-ill patients, is still lacking. The decision-making strategy in the context of fever management in critical care must be supported by single case assessment. This chapter summarizes the main physiological mechanisms of temperature control that physicians should consider when dealing with fever or deliberate hypothermia and analyses the main evidence in the role of fever in the critically ill in order to help bedside clinical strategy.
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- Section 1 ICU organization and management
- Section 2 Pharmacotherapeutics
- Section 3 Resuscitation
- Section 4 The respiratory system
- Section 5 The cardiovascular system
- Section 6 The gastrointestinal system
- Section 7 Nutrition
- Section 8 The renal system
- Section 9 The neurological system
- Section 10 The metabolic and endocrine systems
- Section 11 The haematological system
- Section 12 The skin and connective tissue
- Section 13 Infection
- Section 14 Inflammation
- Section 15 Poisoning
- Section 16 Trauma
- Section 17 Physical disorders
- Part 17.1 Drowning
- Part 17.2 Electrocution
- Part 17.3 Altitude- and depth-related disorders
- Part 17.4 Temperature related disorders
- Chapter 352 Pathophysiology and management of fever
- Chapter 353 Pathophysiology and management of hyperthermia
- Chapter 354 Pathophysiology and management of hypothermia
- Part 17.5 Rhabdomyolysis
- Section 18 Pain and sedation
- Section 19 General surgical and obstetric intensive care
- Section 20 Specialized intensive care
- Section 21 Recovery from critical illness
- Section 22 End-of-life care