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date: 05 July 2022

Sepsis is the presence of a known or suspected infection and a systemic inflammatory response. Severe sepsis is sepsis with acute organ dysfunction. Septic shock is a subset of severe sepsis characterized by systemic arterial hypotension or occult hypoperfusion. Severe sepsis is common, affecting more than 750 000 individuals in the United States each year with a hospital mortality of about 30%.Severe sepsis is a medical emergency that requires early identification, prompt evaluation, and treatment. The signs and symptoms of sepsis are influenced by the virulence of the pathogen, the portal of entry, the degree of organ dysfunction as well as the susceptibility and response of the host.

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