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The metabolic and endocrine systems 

The metabolic and endocrine systems
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date: 20 February 2020

The endocrine system describes an array of chemical signals (hormones). Working in concert with the nervous system, the endocrine system forms a complex neurohumoral network, communicating changes in the environment to facilitate adaptive responses and serving to integrate those responses in a coherent, coordinated manner. The endocrine system has inherent rhythmicity, which has important implications for the integration and coordination of metabolism, and how we measure endocrine signals in clinical settings. At a cellular level, hormone action is mediated through a series of discrete, but interacting signal transduction pathways. This chapter outlines a functional design approach to endocrinology; providing a framework covering the principles of hormone regulation and hormone action—critical for understanding the role of the endocrine system in physiology and pathophysiology.

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