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Setting rate, volume, and time in ventilatory support 

Setting rate, volume, and time in ventilatory support
Setting rate, volume, and time in ventilatory support

Charles M. Oliver

and S. Ramani Moonesinghe

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date: 19 February 2020

Ventilator rate, volume, and time parameters are interrelated directly, mechanically, and physiologically, and interactions between intrinsic pulmonary physio-mechanics, pathology and the effects of mechanical ventilation complex. The physiological consequences of mechanical ventilation and risks of ventilator-induced trauma may be exacerbated by lung pathology. Programming of ventilator parameters should be considered within the context of an individualized ventilatory strategy to achieve adequate gas exchange, while minimizing attendant risks of mechanical ventilation. Recommended strategies should be modified within accepted limits to mitigate disease-specific risks. Parameters should subsequently be titrated against blood gas- and ventilator-derived targets, and other clinical variables.

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