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Continuous haemofiltration techniques in the critically ill 

Continuous haemofiltration techniques in the critically ill
Chapter:
Continuous haemofiltration techniques in the critically ill
Author(s):

Zaccaria Ricci

and Claudio Ronco

DOI:
10.1093/med/9780199600830.003.0214
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date: 24 February 2020

Continuous renal replacement therapy (CRRT) is currently considered the mainstay of treatment for severe acute kidney injury. CRRT helps in restoration of fluid balance, control of hyperazotaemia, acid-base imbalances, and electrolyte abnormalities. Most importantly, due to its gradual, low efficiency, continuous solute and water removal, it ensures haemodynamic stability in critically-ill patients being treated with a high level of inotropic support and those with cardiovascular failure. This chapter will discuss the different solute removal techniques (diffusion and convection) and CRRT modalities (ultrafiltration, haemofiltration and haemodialysis). Insights on CRRT prescription and anticoagulation regimens will also be described on the light of the most recent clinical evidence.

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