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Monitoring renal function in the critically ill 

Monitoring renal function in the critically ill
Chapter:
Monitoring renal function in the critically ill
Author(s):

Paul M. Palevsky

DOI:
10.1093/med/9780199600830.003.0209
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date: 01 August 2021

Renal function needs to be monitored in critically-ill patients to detect changes in glomerular filtration rate (GFR) and promptly diagnosis acute kidney injury (AKI). In the absence of reliable bedside techniques for the assessment of GFR, continuous monitoring of urine output and frequent assessment of serum creatinine levels remain the cornerstone of renal functional monitoring. Calculated estimations of GFR should not be relied upon in critically-ill patients, particularly if kidney function is not stable. The role of serum cystatin C as a marker of GFR and biomarkers of tubular injury in routine monitoring of kidney function is uncertain.

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