- Section 1 ICU organization and management
- Section 2 Pharmacotherapeutics
- Section 3 Resuscitation
- Section 4 The respiratory system
- Section 5 The cardiovascular system
- Section 6 The gastrointestinal system
- Part 6.1 Physiology
- Part 6.2 Gastrointestinal monitoring
- Part 6.3 Gastrointestinal haemorrhage
- Part 6.4 Disordered gastric motility
- Part 6.5 The acute abdomen in the ICU
- Part 6.6 Pancreatitis
- Part 6.7 Jaundice
- Part 6.8 Acute hepatic failure
- Part 6.9 Acute on chronic hepatic failure
- Chapter 199 Pathophysiology, diagnosis, and assessment of acute or chronic hepatic failure
- Chapter 200 Management of acute or chronic hepatic failure in the critically ill
- Section 7 Nutrition
- Section 8 The renal system
- Section 9 The neurological system
- Section 10 The metabolic and endocrine systems
- Section 11 The haematological system
- Section 12 The skin and connective tissue
- Section 13 Infection
- Section 14 Inflammation
- Section 15 Poisoning
- Section 16 Trauma
- Section 17 Physical disorders
- Section 18 Pain and sedation
- Section 19 General surgical and obstetric intensive care
- Section 20 Specialized intensive care
- Section 21 Recovery from critical illness
- Section 22 End-of-life care
(p. 940) Pathophysiology, diagnosis, and assessment of acute or chronic hepatic failure
- Chapter:
- (p. 940) Pathophysiology, diagnosis, and assessment of acute or chronic hepatic failure
- Author(s):
Alastair O’Brien
- DOI:
- 10.1093/med/9780199600830.003.0199
Cirrhosis is an increasing problem and prognosis following intensive care unit admission is poor. Acute on chronic liver failure (ACLF) is a separate entity to cirrhosis with organ failure at the core of this syndrome. Infection and the associated systemic inflammatory responses are the most important precipitants of ACLF. Clinical assessment should follow the standard airway breathing circulation disability exposure approach to the critically-ill patient.
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- Section 1 ICU organization and management
- Section 2 Pharmacotherapeutics
- Section 3 Resuscitation
- Section 4 The respiratory system
- Section 5 The cardiovascular system
- Section 6 The gastrointestinal system
- Part 6.1 Physiology
- Part 6.2 Gastrointestinal monitoring
- Part 6.3 Gastrointestinal haemorrhage
- Part 6.4 Disordered gastric motility
- Part 6.5 The acute abdomen in the ICU
- Part 6.6 Pancreatitis
- Part 6.7 Jaundice
- Part 6.8 Acute hepatic failure
- Part 6.9 Acute on chronic hepatic failure
- Chapter 199 Pathophysiology, diagnosis, and assessment of acute or chronic hepatic failure
- Chapter 200 Management of acute or chronic hepatic failure in the critically ill
- Section 7 Nutrition
- Section 8 The renal system
- Section 9 The neurological system
- Section 10 The metabolic and endocrine systems
- Section 11 The haematological system
- Section 12 The skin and connective tissue
- Section 13 Infection
- Section 14 Inflammation
- Section 15 Poisoning
- Section 16 Trauma
- Section 17 Physical disorders
- Section 18 Pain and sedation
- Section 19 General surgical and obstetric intensive care
- Section 20 Specialized intensive care
- Section 21 Recovery from critical illness
- Section 22 End-of-life care