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Vomiting and large nasogastric aspirates in the critically ill 

Vomiting and large nasogastric aspirates in the critically ill
Vomiting and large nasogastric aspirates in the critically ill

Tong J. Gan

and John T. Lemm

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date: 05 July 2022

A wide range of conditions can cause nausea and vomiting, making it a common occurrence in the critically ill. A deeper understanding of the pathophysiology of vomiting has led to the emergence of effective anti-emetics, each targeting a specific neurotransmitter in the emetic pathway. Serotonin antagonists are the first line anti-emetic of choice for most cases of nausea and vomiting due to their efficacy and favourable side effect profile. Large nasogastric aspirates are commonly encountered in the critically ill, and must be managed aggressively in order to prevent delays in enteral nutrition. Management of large gastric aspirates involves gastric drainage, prokinetic agents, and if necessary, post-pyloric feeding.

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