- Foreword
- Preface
- Acknowledgements
- Contributors
- List of abbreviations
- Part I Coronary heart disease
- Chapter 1 Epidemiology, outcomes, and quality of care
- Chapter 2 Lipids and cardiovascular disease
- Chapter 3 Myocardial ischaemia
- Chapter 4 Thrombosis, haemostasis, and platelet biology
- Chapter 5 Medical versus invasive management of coronary heart disease
- Chapter 6 Percutaneous coronary intervention
- Chapter 7 Percutaneous coronary intervention versus coronary artery bypass graft surgery
- Part II Cardiac electrophysiology and heart rhythm disturbances
- Chapter 8 Epidemiology and molecular foundation
- Chapter 9 Atrial fibrillation
- Chapter 10 Interventional electrophysiology
- Chapter 11 Anti-arrhythmic drug therapy
- Part III Heart failure
- Chapter 12 Epidemiology
- Chapter 13 Medical management
- Chapter 14 Cardiac resynchronization therapy
- Chapter 15 Non-ischaemic cardiomyopathy
- Chapter 16 Cardiac failure and transplantation
- Part IV Hypertension
- Chapter 17 Systemic arterial hypertension
- Chapter 18 Pulmonary arterial hypertension
- Part V Valvular heart disease
- Chapter 19 Epidemiology and intervention
- Chapter 20 Endocarditis
- Part VI Cardiac imaging
- Chapter 21 Echocardiography
- Chapter 22 Cardiovascular magnetic resonance
- Chapter 23 Cardiac computed tomography
- Part VII Congenital heart disease
- Chapter 24 Congenital heart disease
- Part VIII Obstetric cardiology
- Chapter 25 Obstetric cardiology
- Part IX Cardiac rehabilitation
- Chapter 26 Cardiac rehabilitation
- Index
(p. 318) (p. 319) Epidemiology and intervention
- Author(s):
Dr Hasan Jilaihawi
, Dr Natalia Briceno
, Dr Joerg Seeburger
, and Friedrich Mohr
- DOI:
- 10.1093/med/9780199594764.003.0019
Within this chapter we have tried to include those papers which have, by themselves, provoked a shift in our understanding of PAH (and one relating to CTEPH) and have moved the field forward. Many of the developments in our understanding have come from work in cardiovascular biology and risen to prominence in piecemeal fashion. As is always the case with research, the uncertainty of experimentation means that many studies in PAH do not stand alone. They are reliant on previous trials or lacked power to show a conclusive result. This has been a continuing problem in PAH trials as ethical considerations restrict the use of mortality end points and the number of cases remain relatively small. However, we have been able to select the most worthy papers in pulmonary hypertension; they demonstrate the ingenuity and originality of the researchers, feature coherent scientific arguments firmly supported by appropriate data, and still stand up as examples of how to conduct research in a rare, but important disease.
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- Foreword
- Preface
- Acknowledgements
- Contributors
- List of abbreviations
- Part I Coronary heart disease
- Chapter 1 Epidemiology, outcomes, and quality of care
- Chapter 2 Lipids and cardiovascular disease
- Chapter 3 Myocardial ischaemia
- Chapter 4 Thrombosis, haemostasis, and platelet biology
- Chapter 5 Medical versus invasive management of coronary heart disease
- Chapter 6 Percutaneous coronary intervention
- Chapter 7 Percutaneous coronary intervention versus coronary artery bypass graft surgery
- Part II Cardiac electrophysiology and heart rhythm disturbances
- Chapter 8 Epidemiology and molecular foundation
- Chapter 9 Atrial fibrillation
- Chapter 10 Interventional electrophysiology
- Chapter 11 Anti-arrhythmic drug therapy
- Part III Heart failure
- Chapter 12 Epidemiology
- Chapter 13 Medical management
- Chapter 14 Cardiac resynchronization therapy
- Chapter 15 Non-ischaemic cardiomyopathy
- Chapter 16 Cardiac failure and transplantation
- Part IV Hypertension
- Chapter 17 Systemic arterial hypertension
- Chapter 18 Pulmonary arterial hypertension
- Part V Valvular heart disease
- Chapter 19 Epidemiology and intervention
- Chapter 20 Endocarditis
- Part VI Cardiac imaging
- Chapter 21 Echocardiography
- Chapter 22 Cardiovascular magnetic resonance
- Chapter 23 Cardiac computed tomography
- Part VII Congenital heart disease
- Chapter 24 Congenital heart disease
- Part VIII Obstetric cardiology
- Chapter 25 Obstetric cardiology
- Part IX Cardiac rehabilitation
- Chapter 26 Cardiac rehabilitation
- Index