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Perioperative cardioprotection 

Perioperative cardioprotection
Chapter:
Perioperative cardioprotection
Author(s):

ML Riess

and JR Kersten

DOI:
10.1093/med/9780199583386.003.0010
Page of

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date: 05 July 2020

Chapter 9 covers perioperative cardioprotection, and features Ten key investigations that highlight the progress in basic and clinical science in this area. In the last 10–15 years, a growing body of evidence has indicated that a variety of pharmacological approaches to decrease cardiovascular risk in patients with coronary artery disease exist including pre- and postconditioning with volatile anaesthetics; the use of noble gases to trigger endogenous cardioprotective signalling without producing loss of consciousness or hypotension; statin therapy to favourably modulate cardiovascular biology that may be both dependent and independent of cholesterol lowering; and judicious use of beta-blockers titrated to achieve maximum efficacy, but with a low risk for adverse effects.

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