- Dedication
- Preface
- Acknowledgements
- Contributors
- Abbreviations
- Chapter 1 Neuromuscular blockade
- Chapter 2 Anaesthetic equipment
- Chapter 3 Inhaled and intravenous anaesthetics
- Chapter 4 Total intravenous anaesthesia
- Chapter 5 Monitoring
- Chapter 6 Optimization
- Chapter 7 Complications of anaesthesia
- Chapter 8 Mechanisms of anaesthesia
- Chapter 9 Local anaesthesia
- Chapter 10 Perioperative cardioprotection
- Chapter 11 Neuroanaesthesia
- Chapter 12 Thoracic anaesthesia
- Chapter 13 Anaesthesia for vascular surgery
- Chapter 14 Anaesthesia for major abdominal surgery
- Chapter 15 Liver transplantation anaesthesia
- Chapter 16 Obstetric anaesthesia
- Chapter 17 Airway management
- Chapter 18 Paediatric anaesthesia
- Chapter 19 Malignant hyperthermia
- Appendix
- Author Index
- Subject Index
(p. 126) (p. 127) Optimization
- Author(s):
MPW Grocott
and MG Mythen
- DOI:
- 10.1093/med/9780199583386.003.0006
Chapter 6 covers optimization, and includes papers that discuss Shoemaker's landmark randomized controlled trial on cardiac output and oxygen delivery values exhibited by major surgery survivors, as well as the haemodynamic monitor to guide fluid, or fluid and drug (intrope or vasodilator) therapy, use of mixed venous oxygen saturation (SvO2) obtained from a central venous catheter as the goal of therapy early (recruited in the emergency room) in severe sepsis or septic shock, and how this result awaits confirmation by the international multicentre studies currently being conducted.
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- Dedication
- Preface
- Acknowledgements
- Contributors
- Abbreviations
- Chapter 1 Neuromuscular blockade
- Chapter 2 Anaesthetic equipment
- Chapter 3 Inhaled and intravenous anaesthetics
- Chapter 4 Total intravenous anaesthesia
- Chapter 5 Monitoring
- Chapter 6 Optimization
- Chapter 7 Complications of anaesthesia
- Chapter 8 Mechanisms of anaesthesia
- Chapter 9 Local anaesthesia
- Chapter 10 Perioperative cardioprotection
- Chapter 11 Neuroanaesthesia
- Chapter 12 Thoracic anaesthesia
- Chapter 13 Anaesthesia for vascular surgery
- Chapter 14 Anaesthesia for major abdominal surgery
- Chapter 15 Liver transplantation anaesthesia
- Chapter 16 Obstetric anaesthesia
- Chapter 17 Airway management
- Chapter 18 Paediatric anaesthesia
- Chapter 19 Malignant hyperthermia
- Appendix
- Author Index
- Subject Index