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Total intravenous anaesthesia 

Total intravenous anaesthesia
Total intravenous anaesthesia

JK Oosterhuis

and AR Absalom

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date: 27 January 2021

Chapter 4 covers total intravenous anaesthesia (TIVA), its modern popularity, the complexities of pharmacokinetics of drug infusions and the benefits of the use of computer simulations in rational choice of opioids for infusions, as well as remifentanil, target-controlled infusion (TCI) technology, the Marsh and the Schnider models for propofol use, and the important advantages of propofol, including the beneficial effects on cerebral haemodynamics and the low incidence of postoperative nausea and vomiting.

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