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Rheumatological complications of renal disease and transplantation 

Rheumatological complications of renal disease and transplantation
Rheumatological complications of renal disease and transplantation

Sharmin Nizam

, Zunaid Karim

, and Paul Emery

Page of

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date: 23 September 2020

1. Both acute and chronic musculoskeletal problems can significantly affect morbidity of renal transplant patients

2. It is important to correct predisposing risk factors of renal osteodystrophy such as hyperparathyroidism

3. Aim for optimization of steroid-sparing immunosuppression to reduce risk of osteopaenia and osteonecrosis.

4. Joint aspiration should always be considered in the case of an acute hot joint.

5. Systemic features (fever, rigors) may be absent in septic joints in patients on immunosuppressants (e.g. post transplant).

6. Gout is more common in renal insufficiency than renal failure/dialysis patients and can occur any time post transplant (even years).

7. Avoid loop and thiazide diuretics if possible to reduce risk of gout.

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