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Inflammation, growth factors, and thrombosis in PAH 

Inflammation, growth factors, and thrombosis in PAH
Chapter:
Inflammation, growth factors, and thrombosis in PAH
Author(s):

Clive Handler

and Gerry Coghlan

DOI:
10.1093/med/9780199572564.003.013
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date: 16 October 2019

Inflammation in PAH 46

Growth factors and inflammation in PAH 46

Cellular factors in PA remodelling 47

Viral and other infectious factors in PAH 47

Thrombosis in PAH 47

Inflammation plays a role in IPAH and CTD-PAH, HIV-PAH, with circulating antinuclear antibody (ANA) and ↑ levels of pro-inflammatory cytokines interleukin (IL)-1 and IL-6. Inflammatory cells and platelets through the serotonin pathway may play a role....

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