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Pathophysiology of PH in non-PAH groups 

Pathophysiology of PH in non-PAH groups
Pathophysiology of PH in non-PAH groups

Clive Handler

and Gerry Coghlan

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date: 30 October 2020

Group 2: PH due to left heart disease 42

Group 3: PH due to lung diseases and/or hypoxia 42

Group 4: CTEPH 43

PH is common in all forms of left heart disease. Any cause of an increase in LVEDP (coronary heart disease, cardiomyopathy, valvular heart disease) results in an increase in LAP, which is transmitted by passive back pressure through the pulmonary veins to the PA (post-capillary PH). The TPG should be <12mmHg. The PVR is usually normal....

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