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- Foreword
- Preface
- Contributors
- Chapter 1 History of pancreas transplantation
- Chapter 2 The nature of the problem: why do we need pancreatic transplantation?
- Chapter 3 Experimental models in whole-organ pancreatic transplantation
- Chapter 4 Indications, patient evaluation, and selection
- Chapter 5 Donor management and selection in pancreas transplantation
- Chapter 6 Procurement and benchwork preparation of the pancreatic graft
- Chapter 7 Pancreas preservation
- Chapter 8 Surgical techniques of pancreas transplantation
- Chapter 9 Immunosuppression for pancreas transplantation
- Chapter 10 Pancreatic rejection: histology, diagnosis, and treatment
- Chapter 11 Surgical complications of pancreas transplantation
- Chapter 12 Medical and urological complications of pancreas and kidney–pancreas transplantation
- Chapter 13 Post-transplant glucose intolerance
- Chapter 14 Long-term metabolic and other consequences of pancreas and islet transplantation
- Chapter 15 Quality issues in pancreas transplantation
- Chapter 16 Pancreas transplants using living donors
- Chapter 17 Pancreas transplant outcomes for United States (US) cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR)
- Chapter 18 Insulin gene therapy
- Chapter 19 A historical view of the development of islet transplantation
- Chapter 20 Fetal and neonatal pancreatic tissue transplantation
- Chapter 21 Experimental approaches to the prevention of islet rejection
- Chapter 22 Suitable donor selection and techniques of islet isolation and purification for human islet-allograft transplantation
- Chapter 23 Outcomes and clinical effectiveness of islet transplantation
- Chapter 24 Islet autotransplantation
- Chapter 25 Approaches to immunological tolerance and potential application in pancreatic islet transplantation
- Chapter 26 History of pancreatic stem cell transplantation and alternative islet sources
- Chapter 27 Stem cell therapy for the treatment of diabetes
- Chapter 28 Future challenges in beta-cell-replacement therapies
- Chapter 29 Beta-cell regeneration in the post-natal pancreas
- Chapter 30 Gene and stem cell therapies for diabetes mellitus
- Index
(p. 483) Future challenges in beta-cell-replacement therapies
(p. 483)
Future challenges in beta-cell-replacement therapies
- Chapter:
- (p. 483) Future challenges in beta-cell-replacement therapies
- Author(s):
Kevin Docherty
and Alan Colman
- DOI:
- 10.1093/med/9780199565863.003.0028
Chapter 28 describes progress towards the development of novel cell-therapy approaches that target the decline in β-cell mass.
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- Foreword
- Preface
- Contributors
- Chapter 1 History of pancreas transplantation
- Chapter 2 The nature of the problem: why do we need pancreatic transplantation?
- Chapter 3 Experimental models in whole-organ pancreatic transplantation
- Chapter 4 Indications, patient evaluation, and selection
- Chapter 5 Donor management and selection in pancreas transplantation
- Chapter 6 Procurement and benchwork preparation of the pancreatic graft
- Chapter 7 Pancreas preservation
- Chapter 8 Surgical techniques of pancreas transplantation
- Chapter 9 Immunosuppression for pancreas transplantation
- Chapter 10 Pancreatic rejection: histology, diagnosis, and treatment
- Chapter 11 Surgical complications of pancreas transplantation
- Chapter 12 Medical and urological complications of pancreas and kidney–pancreas transplantation
- Chapter 13 Post-transplant glucose intolerance
- Chapter 14 Long-term metabolic and other consequences of pancreas and islet transplantation
- Chapter 15 Quality issues in pancreas transplantation
- Chapter 16 Pancreas transplants using living donors
- Chapter 17 Pancreas transplant outcomes for United States (US) cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR)
- Chapter 18 Insulin gene therapy
- Chapter 19 A historical view of the development of islet transplantation
- Chapter 20 Fetal and neonatal pancreatic tissue transplantation
- Chapter 21 Experimental approaches to the prevention of islet rejection
- Chapter 22 Suitable donor selection and techniques of islet isolation and purification for human islet-allograft transplantation
- Chapter 23 Outcomes and clinical effectiveness of islet transplantation
- Chapter 24 Islet autotransplantation
- Chapter 25 Approaches to immunological tolerance and potential application in pancreatic islet transplantation
- Chapter 26 History of pancreatic stem cell transplantation and alternative islet sources
- Chapter 27 Stem cell therapy for the treatment of diabetes
- Chapter 28 Future challenges in beta-cell-replacement therapies
- Chapter 29 Beta-cell regeneration in the post-natal pancreas
- Chapter 30 Gene and stem cell therapies for diabetes mellitus
- Index